Predictive Oncology (POAI), a biotechnology firm specializing in AI-driven most cancers analysis, has introduced a $344.4 million digital asset treasury centered on Aethir’s ATH token, marking the primary time a Nasdaq-listed firm will maintain and actively handle tokens from a Decentralized Bodily Infrastructure Community (DePIN).
The capital technique was developed with steering from DNA Fund, a Web3 funding and advisory firm, and BTIG, which served as the location agent, Predictive Oncology disclosed Monday. It was structured as two concurrent personal placements in public fairness (PIPEs), combining money funding with a crypto PIPE involving in-kind contributions of ATH tokens, DNA Fund stated in a separate announcement.
The construction permits Predictive Oncology to document tokenized DePIN infrastructure as a steadiness sheet asset, introducing a hybrid financing mannequin that connects conventional fairness markets with decentralized computing networks. The ATH treasury might be tied on to Aethir’s decentralized GPU infrastructure.
Aethir is a decentralized cloud community that gives GPU infrastructure for AI, high-performance computing and gaming purposes. The community makes use of blockchain know-how to coordinate and distribute entry to bodily compute sources, positioning it as a key participant within the DePIN market.
The community’s native asset, ATH, is at present buying and selling at below $0.06 with a market capitalization of about $2.3 billion, in line with CoinMarketCap. ATH’s 24-hour buying and selling quantity has elevated by greater than 330%, seemingly because of the Predictive Oncology treasury announcement.

Aethir (ATH) token worth. Supply: CoinMarketCap
Associated: VC Roundup: Traders proceed to again DePIN, Web3 gaming, layer-1 RWAs
Predictive Oncology’s blockchain pivot lifts inventory
Predictive Oncology’s transfer into decentralized infrastructure drew early consideration from traders, with shares surging greater than 70% on Monday following the announcement of its digital asset treasury. The rally pushed the inventory to its highest stage since March.

Predictive Oncology (POIA) inventory worth. Supply: Yahoo Finance
Earlier than the announcement, Predictive Oncology spent the final two years buying and selling as a penny inventory with restricted income and a historical past of quarterly losses. The corporate reported simply $2,682 in income for the second quarter of 2025 and $110,310 within the first quarter, alongside web losses exceeding $2 million in every interval.
In its most up-to-date quarter, Predictive Oncology raised roughly $586,000 by an at-the-market providing facility to assist fund operations.
In March, the corporate bought its Skyline Medical division, which manufactured an automatic fluid waste administration gadget utilized in medical facilities, as a part of a broader technique to chop bills and refocus on AI-driven drug discovery.
Predictive Oncology’s new technique positions it amongst a rising group of small-cap and microcap companies pivoting towards digital asset treasury fashions. In July, the previous biotech firm 180 Life Sciences rebranded as ETHZilla and introduced plans to build up Ether (ETH) as a treasury asset.
Different publicly traded firms, together with Mill Metropolis Ventures (MCVT), Nature’s Miracle (NMHI), Upexi (UPXI), Helius Medical Applied sciences (HSDT) and AVAX One, previously AgriFORCE Rising Methods, have made related strikes to combine crypto belongings into their steadiness sheets.
Analysts at Normal Chartered have cautioned that digital asset treasury firms may face a valuation squeeze as market web asset values (mNAVs), which evaluate an organization’s enterprise worth to its crypto holdings, proceed to say no.

The biggest digital asset treasury (DAT) firms have skilled mNAV compression in latest months. Supply: Normal Chartered
“We see market saturation as the primary driver of latest mNAV compression,” Normal Chartered wrote, referring to the speedy improve in firms adopting digital asset treasury methods this 12 months.
Associated: After $400M splurge, ETH treasurer eyes inventory buyback amid leverage issues

